Genetic variation related to caffeine metabolism or response during exercise
نویسندگان
چکیده
Methods We examined whether a panel of 25 SNPs in 19 genes that might be related to caffeine metabolism or response modified exercise performance, or were associated with any physiologic outcomes during exercise. Subjects were trained male cyclists (n = 33) who underwent a doubleblind placebo-controlled crossover trial to test the effects of caffeine (6 mg/kg) on various performance parameters during a computer-simulated 40 km time trial. The 25 SNPs were genotyped using the Sequenom MassARRAY system, and caffeine-genotype interactions on time trial time, VO2 max, heart rate, respiratory exchange ratio and rate of perceived exertion were assessed using repeated measures analysis of variance.
منابع مشابه
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